<p class="articleBody_abstractText">Delivery of proteins into cells may alter cellular functions as various proteins are involved in cellular signaling by activating or deactivating the corresponding pathways and, therefore, can be used in cancer therapy. In this study, we have demonstrated for the first time that PEGylated graphene oxide (GO) can be exploited as a nanovector for efficient delivery of proteins into cells. In this approach, GO was functionalized with amine-terminated 6-armed polyethylene glycol (PEG) molecules, thereby providing GO with proper physiological stability and biocompatibility. Proteins were then loaded onto PEG-grafted GO (GO-PEG) with high payload via noncovalent interactions. GO-PEG could deliver proteins to cy...
We have synthesized a new multifunctional graphene oxide as a drug carrier targeting to hepatocarcin...
Graphene oxide (GO) is one of the most explored nanomaterials in recent years. It has numerous biome...
Engineered nanomaterials promise to transform medicine at the bio-nano interface. However, it is imp...
Delivery of proteins into cells may alter cellular functions as various proteins are involved in cel...
Graphene oxide (GO) has attracted huge interest in the area of biomedical application due to its uni...
Coating graphene oxide nanoflakes with cationic lipids leads to highly homogeneous nanoparticles (GO...
Purpose: Genetic diseases can be the result of genetic dysfunctions that happen due to some inhibito...
Graphene has emerged as an interesting compound because of its drug delivery potential. It is useful...
Graphene, a single layer of sp2 -hybridized carbon atoms arranged in a honeycomb two-dimensional (2-...
Polyethylene glycol (PEG) is a gold standard against protein fouling. However, recent studies have r...
Nanomaterials hold potential of altering the interaction between therapeutic molecules and target ce...
Graphene oxide has unique physiochemical properties, showing great potential in biomedical applicati...
Graphene oxide has unique physiochemical properties, showing great potential in biomedical applicati...
An effective strategy to inhibit endocytosis in cancer cells is presented where modified net-type gr...
Chemotherapeutics such as platinum-based drugs are commonly used to treat several cancer types, but ...
We have synthesized a new multifunctional graphene oxide as a drug carrier targeting to hepatocarcin...
Graphene oxide (GO) is one of the most explored nanomaterials in recent years. It has numerous biome...
Engineered nanomaterials promise to transform medicine at the bio-nano interface. However, it is imp...
Delivery of proteins into cells may alter cellular functions as various proteins are involved in cel...
Graphene oxide (GO) has attracted huge interest in the area of biomedical application due to its uni...
Coating graphene oxide nanoflakes with cationic lipids leads to highly homogeneous nanoparticles (GO...
Purpose: Genetic diseases can be the result of genetic dysfunctions that happen due to some inhibito...
Graphene has emerged as an interesting compound because of its drug delivery potential. It is useful...
Graphene, a single layer of sp2 -hybridized carbon atoms arranged in a honeycomb two-dimensional (2-...
Polyethylene glycol (PEG) is a gold standard against protein fouling. However, recent studies have r...
Nanomaterials hold potential of altering the interaction between therapeutic molecules and target ce...
Graphene oxide has unique physiochemical properties, showing great potential in biomedical applicati...
Graphene oxide has unique physiochemical properties, showing great potential in biomedical applicati...
An effective strategy to inhibit endocytosis in cancer cells is presented where modified net-type gr...
Chemotherapeutics such as platinum-based drugs are commonly used to treat several cancer types, but ...
We have synthesized a new multifunctional graphene oxide as a drug carrier targeting to hepatocarcin...
Graphene oxide (GO) is one of the most explored nanomaterials in recent years. It has numerous biome...
Engineered nanomaterials promise to transform medicine at the bio-nano interface. However, it is imp...