High vitamin B12 level

Vitamin B12/cobalamin functions as an important co-enzyme in the human body and is essential forpurine and pyrimidine synthesis. Vitamin B12 deficiency is a very well recognized clinical entity but the conditions leading to elevated levels of vitamin B12 are generally not; hence the purpose of this article is to discuss such etiologies. Understanding the mechanisms will necessitate a brief review of vitamin B12 metabolism, presented below