Modern operating systems have been designed around the hypotheses that (a) memory is both byte-addressable and volatile and (b) storage is block addressable and persistent. The arrival of new Persistent Memory (PM) technologies, has made these assumptions obsolete. Despite much of the recent work in this space, the need for consistently sharing PM data across multiple applications remains an urgent, unsolved problem. Furthermore, the availability of simple yet powerful operating system support remains elusive. In this dissertation, we propose and build The Region System – a high-performance operating system stack for PM that implements usable consistency and persistence for application data. The region system provides support for consistent...