We provide a number of algorithmic results for the following family of problems: For a given binary m x n matrix A and a nonnegative integer k, decide whether there is a "simple" binary matrix B which differs from A in at most k entries. For an integer r, the "simplicity" of B is characterized as follows. - Binary r-Means: Matrix B has at most r different columns. This problem is known to be NP-complete already for r=2. We show that the problem is solvable in time 2^{O(k log k)}*(nm)^O(1) and thus is fixed-parameter tractable parameterized by k. We also complement this result by showing that when being parameterized by r and k, the problem admits an algorithm of running time 2^{O(r^{3/2}* sqrt{k log k})}(nm)^O(1), which is subexponential in...