Understanding recognition and self-assembly in biology using the chemist's toolbox: insight into medicinal chemistry
- Quirolo, Zulma Beatriz
- Benedini, Luciano Alejandro
- Sequeira, María Alejandra
- Herrera, Maria Georgina
- Veuthey, Tania Vanesa
- Dodero, Veronica Isabel
DOIAbstract
Medicinal chemistry is intimately connected with basic science such as organic synthesis, chemical biology and biophysical chemistry among other disciplines. The reason of such connections is due to the power of organic synthesis to provide designed molecules; chemical biology to give tools to discover biological and/or pathological pathways and biophysical chemistry which provides the techniques to characterize and the theoretical background to understand molecular behaviour. The present review provides some selective examples of these research areas. Initially, template dsDNA organic synthesis and the spatio-temporal control of transcription are presenting following by the supramolecular entities used in drug delivery, such as liposomes a...
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