Clade 8 and clade 6 strains of Escherichia coli O157:H7 from cattle in Argentina have hypervirulent-like phenotypes
- Amigo, Natalia
- Mercado, Elsa Cristina
- Bentancor, Adriana Beatriz
- Singh, Pallavi
- Vilte, Daniel
- Gerhardt, Elizabeth
- Zotta, Elsa
- Ibarra, Cristina Adriana
- Manning, Shannon D.
- Larzabal, Mariano
- Cataldi, Ángel Adrián
DOIAbstract
The hemolytic uremic syndrome (HUS) whose main causative agent is enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a disease that mainly affects children under 5 years of age. Argentina is the country with the highest incidence of HUS in the world. Cattle are a major reservoir and source of infection with E. coli O157:H7. To date, the epidemiological factors that contribute to its prevalence are poorly understood. Single nucleotide polymorphism (SNP) typing has helped to define nine E. coli O157:H7 clades and the clade 8 strains were associated with most of the cases of severe disease. In this study, eight randomly selected isolates of EHEC O157:H7 from cattle in Argentina were studied as well as two human isolates. Four of them were cl...
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