Delivery of recombinant vaccines against bovine herpesvirus type 1 and Babesia bovis to mice using liposomes derived from egg yolk lipids

Rodriguez, Anabel Elisa
Zamorano, Patricia Ines
Wilkowsky, Silvina Elizabeth
Torrá, Florencia Lucia
Ferreri, Lucas
Dominguez, Mariana Gabriela
Jacobsen, Monica Ofelia

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Publication date

June 2013

DOI

10.1016/j.tvjl.2012.10.036

Publisher

Elsevier BV

ISSN

1090-0233

Journal

The Veterinary Journal

Citation count (estimate)

Abstract

Liposomes prepared from total egg yolk lipid extracts were used to deliver experimental DNA vaccines to mice consisting of pCI-neo plasmids encoding bovine herpesvirus type 1 (BoHV-1) gD or Babesia bovis MSA-2c. A significantly higher proportion of mice in the B. bovis MSA-2c group, but not those in the BoHV-1 gD group, developed detectable immunoglobulin G responses when vaccinated with liposome encapsulated DNA in comparison with mice vaccinated with naked DNA. In both groups, antibody titres were similar between mice vaccinated with liposome encapsulated DNA and naked DNA.Fil: Rodriguez, Anabel Elisa. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; ...

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Delivery of recombinant vaccines against bovine herpesvirus type 1 and Babesia bovis to mice using liposomes derived from egg yolk lipids

Abstract

Extracted data

Delivery of recombinant vaccines against bovine herpesvirus type 1 and Babesia bovis to mice using liposomes derived from egg yolk lipids

Abstract

Extracted data

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