QnrE1, a member of a new family of plasmid-located quinolone resistance genes, originated from the chromosome of enterobacter species
- Albornoz, Ezequiel Pablo
- Tijet, Nathalie
- de Belder, Denise Gisele
- Gómez, Sonia Alejandra
- Martino, Florencia
- Corso, Alejandra
- Melano, Roberto G.
- Petroni, Alejandro
DOIAbstract
qnrE1, found in a clinical Klebsiella pneumoniae isolate, was undetectable by PCR assays used for the six qnr families. qnrE1 was located on a conjugative plasmid (ca. 185 kb) and differed from qnrB alleles by 25%. Phylogenetic reconstructions of qnr genes and proteins and analysis of the qnrE1 surroundings showed that this gene belongs to a new qnr family and was likely mobilized by ISEcp1 from the chromosome of Enterobacter spp. to plasmids of K. pneumoniae.Fil: Albornoz, Ezequiel Pablo. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas; ArgentinaFil: Tijet, Nathalie. Public Health Ontario Laboratory; CanadáFil: de Belder, Denise...
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