IgG subclasses of FVIII inhibitors in an argentine cohort of severe hemophilia A patients: Analysis by flow cytometry
- Irigoyen, María Belén
- Primiani, L.
- Felippo, Marta Elena
- Candela, Miguel
- Elizalde, María Marta
- Galassi, Nora Virginia
DOIAbstract
FVIII inhibitors consist of a polyclonal population of antibodies. Previous studies have demonstrated different distribution of IgG subclasses. IgG4 was associated to high level of FVIII inhibitors and failure of Immune Tolerance Induction (ITI) treatment. This study monitored the relative distribution of IgG subclasses of anti-FVIII in Severe Hemophilia A (SHA) patients.Fil: Irigoyen, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; ArgentinaFil: Primiani, L.. Fundacion Argentina de Hemofilia; ArgentinaFil: Felippo, Marta Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto d...
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