In this paper a new flow resistance equation for open channel flow, based on the integration of a power velocity profile, was tested for gravel bed channels. First this flow resistance equation, theoretically deduced by dimensional analysis and incomplete self-similarity condition, was reported. Then a relationship between the Γ function of the velocity profile, the channel slope and the Froude number was calibrated by the available laboratory measurements of flow velocity, water depth and bed slope carried out in 416 flume experimental runs with a gravel bed. Then the relationship for estimating Γ function and the theoretical resistance equation was tested by 83 independent flume measurements. The analysis also showed that the proposed flo...