Measurements of skeletal muscle mass and power are positively related with a Mediterranean dietary pattern in women

Purpose: The loss of skeletal muscle mass, strength and function with age are contributing risk factors for the onset of sarcopenia, frailty, osteoporosis, fractures and mortality. Nutrition may affect the progression and trajectory of these changes in skeletal muscle but the role of the micronutrient rich Mediterranean Diet (MD) has hardly been investigated in relation to these muscle outcomes. Methods: We examined associations between the MD Score (MDS) and FFM% (fat free mass/weight*100), FFMI (fat free mass/height2), hand grip strength and leg explosive power (LEP, watts/kg) in a cross sectional study in 2570 women aged 18-79 years from the TwinsUK study. Measurements of body composition were made using dual-energy X-ray absorptiometry and dietary intake assessed by a food frequency questionnaire. FFM%, FFMI, grip strength and LEP were compared across quartiles of the MDS after adjustment for covariates, with CRP was measured in a subgroup (N=1658). Results: Higher adherence to the MDS was positively associated with measurements of muscle outcomes, with significant differences of 1.7% for FFM% and 9.6% for LEP (P trend