Pulmonary arterial hypertension (PAH) develops in 7-12% of patients with systemic sclerosis (SSc) and is associated with a 3 year survival of 52%. Early detection by screening is therefore recommended for all patients with SSc. Historically, screening has been performed using echocardiography and measurement of gas transfer. More recently the DETECT protocol, using a combination of biomarkers (including N-terminal pro-brain natriuretic peptide) and clinical parameters, has been developed. The optimal method of screening for PAH with high sensitivity and specificity is, however, not clear. Protein expression differences between different SSc disease phenotypes have been reported, and include alterations in concentration of NT-proBNP, endogli...
Rahul G Argula,1 Celine Ward,2 Carol Feghali-Bostwick2 1Department of Medicine, Division of Pulmonar...
Systemic sclerosis (SSc) is a rare disease, with unfavorable clinical course and prognosis, characte...
Pulmonary hypertension (PH) commonly affects patients with systemic sclerosis (SSc) and is associate...
Pulmonary arterial hypertension (PAH) develops in 7–12% of patients with systemic sclerosis (SSc) an...
© 2013 Dr. Vivek Pramodchandra ThakkarSystemic sclerosis (SSc) is a complex disease characterised by...
Achieving the diagnosis of pulmonary hypertension (PH) is difficult as, given the non-specific natur...
Pulmonary arterial hypertension (PAH) is a severe complication of systemic sclerosis (SSc) associate...
Pulmonary arterial hypertension (PAH) is a devastating complication of Systemic Sclerosis (SSc). Scr...
<p><b>Objective</b>: To identify circulating angiogenic and inflammatory biomarkers with potential i...
Pulmonary arterial hypertension (PAH) is a common complication for individuals with limited systemic...
Pulmonary arterial hypertension (PAH) carries a high morbidity and mortality burden in Systemic Scle...
Systemic sclerosis (SSc; scleroderma) is a chronic multisystem autoimmune disease that includes prom...
Introduction: Pulmonary arterial hypertension is a major cause of mortality in systemic sclerosis. N...
Pulmonary arterial hypertension (PAH) is a common complication of systemic sclerosis (SSc) with high...
INTRODUCTION: Pulmonary arterial hypertension is a major cause of mortality in systemic sclerosis. N...
Rahul G Argula,1 Celine Ward,2 Carol Feghali-Bostwick2 1Department of Medicine, Division of Pulmonar...
Systemic sclerosis (SSc) is a rare disease, with unfavorable clinical course and prognosis, characte...
Pulmonary hypertension (PH) commonly affects patients with systemic sclerosis (SSc) and is associate...
Pulmonary arterial hypertension (PAH) develops in 7–12% of patients with systemic sclerosis (SSc) an...
© 2013 Dr. Vivek Pramodchandra ThakkarSystemic sclerosis (SSc) is a complex disease characterised by...
Achieving the diagnosis of pulmonary hypertension (PH) is difficult as, given the non-specific natur...
Pulmonary arterial hypertension (PAH) is a severe complication of systemic sclerosis (SSc) associate...
Pulmonary arterial hypertension (PAH) is a devastating complication of Systemic Sclerosis (SSc). Scr...
<p><b>Objective</b>: To identify circulating angiogenic and inflammatory biomarkers with potential i...
Pulmonary arterial hypertension (PAH) is a common complication for individuals with limited systemic...
Pulmonary arterial hypertension (PAH) carries a high morbidity and mortality burden in Systemic Scle...
Systemic sclerosis (SSc; scleroderma) is a chronic multisystem autoimmune disease that includes prom...
Introduction: Pulmonary arterial hypertension is a major cause of mortality in systemic sclerosis. N...
Pulmonary arterial hypertension (PAH) is a common complication of systemic sclerosis (SSc) with high...
INTRODUCTION: Pulmonary arterial hypertension is a major cause of mortality in systemic sclerosis. N...
Rahul G Argula,1 Celine Ward,2 Carol Feghali-Bostwick2 1Department of Medicine, Division of Pulmonar...
Systemic sclerosis (SSc) is a rare disease, with unfavorable clinical course and prognosis, characte...
Pulmonary hypertension (PH) commonly affects patients with systemic sclerosis (SSc) and is associate...