Early histological and functional study of radial optic neurotomy outcomes in normal rat eyes
- Belforte, Nicolás Adalberto
- Sande Casal, Pablo Horacio
- Dorfman, Damián
- Croxatto, Juan Oscar
- Rosenstein, Ruth Estela
DOIAbstract
BACKGROUND: Radial optic neurotomy (RON) has been proposed as a treatment for central retinal vein occlusion. However, it is still under debate whether RON would be an adequate treatment or a dangerous procedure, and persuasive animal studies are lacking. The aim of this study was to analyze the early histologic and functional outcomes of RON in normal rat eyes. METHODS: Radial optic neurotomy was performed by cutting into the optic nerve edge at the nasal hemisphere, while the contralateral eye underwent a sham procedure. The retinal function was assessed by scotopic electroretinography, and the visual pathway was assessed by flash visual evoked potentials. Intraocular pressure was assessed with a tonometer, the pupillary light reflex was ...
Add to ORKG