Recent work on joint kinematics indicates that the finite centroid (centre of rotation) and the finite helical axis (axis of rotation, screw axis, twist axis) are highly susceptible to measurement errors when they are experimentally determined from landmark position data. This paper presents an analytical model to describe these effects under isotropic conditions for the measurement errors and for the spatial landmark distribution. It appears that the position and direction errors are inversely proportional to the rotation magnitude, and that they are much more error-prone than the relatively well-determined rotation and translation magnitudes. Furthermore, the direction and rotation magnitude errors are inversely proportional to the landma...