Aspergillus terreus infections are difficult to treat because of the intrinsic resistance to amphotericin B, and higher mortality compared to infections caused by other Aspergillus species. The aim of the present study was to determine the in vitro antifungal activity of amphotericin B and 11 comparators against clinical (n = 36) and environmental (n = 45) A. terreus isolates. In vitro antifungal susceptibility was performed using the CLSI M38-A2 procedure. Amphotericin B exhibited the highest MICs (MIC range, 0.125-4 mug/mL; MIC90 , 2 mug/mL), followed by terbinafine (MIC range, 0.002-1 mug/mL; MIC90 , 1 mug/mL). Only one isolate (1/81) showed amphotericin B MIC above the epidemiologic cut-off value (ECV; 4 mug/mL). None of the isolates ha...
Conventional MIC testing of amphotericin B results in narrow MIC ranges challenging the detection of...
Some environmental Aspergillus spp. isolates have been described as resistant to antifungals, potent...
We compared the in vitro pharmacodynamics of amphotericin B, itraconazole, and voriconazole against ...
Item does not contain fulltextAspergillus terreus infections are difficult to treat because of the i...
Although there is evidence that liposomal amphotericin B (AmBisome) is non-inferior to amphotericin ...
International audienceAspergillus section Terrei is a species complex currently comprised of 14 cryp...
Objectives: To study the susceptibility patterns of clinical isolates of Aspergillus species to amph...
Antifungal agents may differ in their fungicidal activities against Aspergillus spp. In order to com...
Item does not contain fulltextThe effect of the medium composition on the fungistatic (MIC) and fung...
The in vitro fungicidal and fungistatic activities of terbinafine were compared with those of itraco...
We analyzed the activities of six antifungal drugs (amphotericin B, itraconazole, voriconazole, posa...
There is little information addressing the phenomena of discrepancy between minimal inhibitory conce...
The in vitro antifungal susceptibility of 77 isolates belonging to different clinically relevant spe...
The in vitro susceptibility of 105 clinical and environmental strains of Aspergillus fumigatus and A...
Aspergillus flavus is the second leading cause of invasive and non-invasive aspergillosis, as well a...
Conventional MIC testing of amphotericin B results in narrow MIC ranges challenging the detection of...
Some environmental Aspergillus spp. isolates have been described as resistant to antifungals, potent...
We compared the in vitro pharmacodynamics of amphotericin B, itraconazole, and voriconazole against ...
Item does not contain fulltextAspergillus terreus infections are difficult to treat because of the i...
Although there is evidence that liposomal amphotericin B (AmBisome) is non-inferior to amphotericin ...
International audienceAspergillus section Terrei is a species complex currently comprised of 14 cryp...
Objectives: To study the susceptibility patterns of clinical isolates of Aspergillus species to amph...
Antifungal agents may differ in their fungicidal activities against Aspergillus spp. In order to com...
Item does not contain fulltextThe effect of the medium composition on the fungistatic (MIC) and fung...
The in vitro fungicidal and fungistatic activities of terbinafine were compared with those of itraco...
We analyzed the activities of six antifungal drugs (amphotericin B, itraconazole, voriconazole, posa...
There is little information addressing the phenomena of discrepancy between minimal inhibitory conce...
The in vitro antifungal susceptibility of 77 isolates belonging to different clinically relevant spe...
The in vitro susceptibility of 105 clinical and environmental strains of Aspergillus fumigatus and A...
Aspergillus flavus is the second leading cause of invasive and non-invasive aspergillosis, as well a...
Conventional MIC testing of amphotericin B results in narrow MIC ranges challenging the detection of...
Some environmental Aspergillus spp. isolates have been described as resistant to antifungals, potent...
We compared the in vitro pharmacodynamics of amphotericin B, itraconazole, and voriconazole against ...