Effect of Risperidone with Ondansetron to Control the Negative and Depressive Symptoms in Schizophrenia

To evaluate the effects of Ondansetron on the negative and depressive symptoms of patients with schizophrenia. A double-blind randomized control trial was conducted in 2016-17 in Lahore. 30 participants were included both in placebo and medicine group. The patients were assessed by using the Positive and Negative Syndrome Scale (PANSS) and Hamilton’s Rating Scale for Depression (HRSD) at baseline and at 12 weeks. The t-test and Chi square test were used to evaluate the data by using SPSS (version 21). The statistical significance was set at P