Analysis of the association of polymorphic markers of dopaminergic (DRD2/ANKK1) and serotonergic (HTR2A) systems in the brain with the personality traits of adolescents

The studies of personality characteristic of young adolescents caused by their genetic predispositions have become very essential in recent years. In our study we have investigated the association of dopamine (D2) and serotonin (2A) receptor genes with personality traits in 360 young adults. We have found the influence of the combination of DRD2/ANKK1 and HTR2A genes on the personality traits measured on Rule-Consciousness and Self-Reliance scales in girls. The significant statistical difference on Self-control scale was established for polymorphism TaqIA of gene DRD2/ANKK1 in boys. Additionally, the differences on Social Boldness scale were observed after stratification of genotypes DRD2/ANKK1 and HTR2A