Complement, a complex system of serum proteins, contributes to host defense through multiple mechanisms. In this issue of Cell Host & Microbe, Sorbara et al. (2018) discovered that cytosolic pathogens opsonized by complement are restricted by autophagy. This unexpected role for complement is important for cell-autonomous immunity in the intestinal mucosa
The human host has evolved elaborate protection mechanisms to prevent infection from the billions of...
Due to the critical role played by autophagy in pathogen clearance, pathogens have developed diverse...
Intracellular bacterial pathogens have evolved many ways to manipulate host cells for successful inf...
Complement, a complex system of serum proteins, contributes to host defense through multiple mechani...
International audienceThe complement system is a major component of innate immunity that participate...
The complement system is a well-characterized cascade of extracellular serum proteins that is activa...
Crohnâ s disease (CD) is a chronic inflammatory condition of the gastrointestinal tract. Susceptib...
The complement system has a well-defined role in deterring blood-borne infections. However, compleme...
Infections with bacteria form an increasing threat for human health. This is mainly due to the fact ...
AbstractThe number of mechanisms that have evolved in microbes to subvert the immune response seems ...
Protection from acute infection requires an immediate response by the host innate immune system. Two...
Bacteria that cause infections pose a great threat to global human health. Because some bacteria are...
The complement system, an evolutionarily ancient component of innate immunity, is capable of protect...
Bacterial outer membrane vesicles (OMVs) enriched with bioactive proteins, toxins, and virulence fac...
The gastrointestinal tract presents a unique challenge to the mucosal immune system, which has to co...
The human host has evolved elaborate protection mechanisms to prevent infection from the billions of...
Due to the critical role played by autophagy in pathogen clearance, pathogens have developed diverse...
Intracellular bacterial pathogens have evolved many ways to manipulate host cells for successful inf...
Complement, a complex system of serum proteins, contributes to host defense through multiple mechani...
International audienceThe complement system is a major component of innate immunity that participate...
The complement system is a well-characterized cascade of extracellular serum proteins that is activa...
Crohnâ s disease (CD) is a chronic inflammatory condition of the gastrointestinal tract. Susceptib...
The complement system has a well-defined role in deterring blood-borne infections. However, compleme...
Infections with bacteria form an increasing threat for human health. This is mainly due to the fact ...
AbstractThe number of mechanisms that have evolved in microbes to subvert the immune response seems ...
Protection from acute infection requires an immediate response by the host innate immune system. Two...
Bacteria that cause infections pose a great threat to global human health. Because some bacteria are...
The complement system, an evolutionarily ancient component of innate immunity, is capable of protect...
Bacterial outer membrane vesicles (OMVs) enriched with bioactive proteins, toxins, and virulence fac...
The gastrointestinal tract presents a unique challenge to the mucosal immune system, which has to co...
The human host has evolved elaborate protection mechanisms to prevent infection from the billions of...
Due to the critical role played by autophagy in pathogen clearance, pathogens have developed diverse...
Intracellular bacterial pathogens have evolved many ways to manipulate host cells for successful inf...
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