Design, Fabrication, and Test of Chaotic Micromixers, Hydrogel Microvalves and pH Regulation Systems

143 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2001.In the last part of the thesis, two integrated microsystems designed to provide self regulation of pH in bioassays are demonstrated. The first system is based on the counterflow microdialysis principle, whereas the second system involves direct addition of an acidic or basic buffer solution into a sample solution. In both systems, a hydrogel component is used as a pH sensor, controller, and valve, simultaneously. Oscillatory modulation of the flow was achieved, and the feasibility of autonomous control of pH in microsystems has been demonstrated.U of I OnlyRestricted to the U of I community idenfinitely during batch ingest of legacy ETD