Add to ORKG111 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2007.The last part of this dissertation centers on combinatorial library design, which is a promising protein engineering method. Despite the fact that several mathematical models have been proposed recently and shown great promise, little is known about their theoretic properties. We have discovered several important properties, and shown how to exploit these results to design powerful algorithms.U of I OnlyRestricted to the U of I community idenfinitely during batch ingest of legacy ETD
Protein design critically tests our understanding of principles that specify the protein folded stat...
For many protein design problems, limited understanding of the relationship between sequence and fun...
To facilitate the design of protein sequences with desired properties, simulation techniques have be...
111 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2007.The last part of this dissert...
Proteins are chains of simple molecules called amino acids. The three-dimensional shape of a protein...
Abstract. Proteins are chains of simple molecules called amino acids. The three-dimensional shape of...
Proteins are chains of simple molecules called amino acids. The three-dimensional shape of a protein...
International audienceProteins are the main active molecules of life. Although natural proteins play...
International audienceProteins are chains of simple molecules called amino acids. The sequence of am...
Motivation: The main challenge for structure-based computational protein design (CPD) remains the co...
The recent emphasis in combinatorial library design has shifted from the design of very large divers...
Computational molecular biology has emerged as one of the most exciting interdisciplinary fields, ri...
<p>This thesis focuses on the development of algorithms that will allow protein design calculations ...
We developed a combinatorial search algorithm which we call best profile search for the global optim...
This is a survey designed for mathematical programming people who do not know molecular biology and ...
Protein design critically tests our understanding of principles that specify the protein folded stat...
For many protein design problems, limited understanding of the relationship between sequence and fun...
To facilitate the design of protein sequences with desired properties, simulation techniques have be...
111 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2007.The last part of this dissert...
Proteins are chains of simple molecules called amino acids. The three-dimensional shape of a protein...
Abstract. Proteins are chains of simple molecules called amino acids. The three-dimensional shape of...
Proteins are chains of simple molecules called amino acids. The three-dimensional shape of a protein...
International audienceProteins are the main active molecules of life. Although natural proteins play...
International audienceProteins are chains of simple molecules called amino acids. The sequence of am...
Motivation: The main challenge for structure-based computational protein design (CPD) remains the co...
The recent emphasis in combinatorial library design has shifted from the design of very large divers...
Computational molecular biology has emerged as one of the most exciting interdisciplinary fields, ri...
<p>This thesis focuses on the development of algorithms that will allow protein design calculations ...
We developed a combinatorial search algorithm which we call best profile search for the global optim...
This is a survey designed for mathematical programming people who do not know molecular biology and ...
Protein design critically tests our understanding of principles that specify the protein folded stat...
For many protein design problems, limited understanding of the relationship between sequence and fun...
To facilitate the design of protein sequences with desired properties, simulation techniques have be...