Lifespan Changes, Sex Differences, and Hormone Effects in the Primary Visual Cortex of the Rat and the Associated Area of the Corpus Callosum, the Splenium

82 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2007.Effects of aging were also investigated in Oc1 and the splenium. Examination of neuron number in aged animals (19-22 months) found that Oc1 was significantly impacted during aging, with both males and females losing neurons (18-20%) between day 90 and old age, maintaining the sex differences in neuron number. However, examination of the splenium in adult (day 120), middle age (12-13 months) and aged (18-26 months) animals showed no age-related deterioration. Instead, the splenium increased in size between adulthood and old age, demonstrating the regionally-specific effects of age in the rat.U of I OnlyRestricted to the U of I community idenfinitely during batch ingest of legacy ETD