Health Psychol

ObjectiveDaily stress processes have been previously linked to health-related outcomes, but implications for longevity remain unclear. The present study examined whether daily stress exposure and/or affective responses to daily stressors predicted mortality risk over a 20-year period. Based on the hypothesis that chronic illness confers vulnerability to deleterious effects of stress, we also examined whether its presence accentuated the association between daily stress processes and later mortality risk.MethodsParticipants were 1,346 middle-aged adults from the survey of Midlife Development in the United States who also completed the National Study of Daily Experiences. Participants reported on their experiences of stress and affect for eight consecutive evenings, and mortality data were collected over the next 20 years, using the National Death Index and other methods.ResultsThere was a positive association between total number of stressors experienced across days and mortality risk. There was also a positive association between increases in negative affect on stressor days relative to non-stressor days and risk for mortality. The presence of a chronic illness moderated this association such that negative affective reactivity predicted mortality risk among individuals with at least one chronic illness, but not among otherwise healthy individuals. This association was independent of sociodemographic characteristics, typical levels of negative affect on non-stressor days, and total number of endorsed stressors.ConclusionThese results suggest that greater increases in negative affect in response to stress in everyday life may have long-term consequences for longevity, particularly for individuals with chronic illness.R01 AG018436/AG/NIA NIH HHSUnited States/R01 HL122328/HL/NHLBI NIH HHSUnited States/U48 DP005004/DP/NCCDPHP CDC HHSUnited States/F32 HL134276/HL/NHLBI NIH HHSUnited States/P01 AG020166/AG/NIA NIH HHSUnited States/U19 AG051426/AG/NIA NIH HHSUnited States