The effect of volume variations on the osteogenic capabilities of autogenous cancellous bone graft in the dog

The radiographic healing patterns of partial cortical ulnar defects receiving different volumes of fresh autogenous cancellous bone graft (ACBG) were compared. Histological sections taken at 8 weeks after ACBG transplantation were planimetrically evaluated for area of total bone, lamellar bone, and woven bone.Nongrafted defects and defects receiving 0.1g of ACBG displayed similar healing trends to each other. Bone production showed maximum increment between 2 and 6 weeks postoperatively. Defects receiving 0.3g and 0.75g of ACBG displayed similar healing trends, with rapid initial bone production and slower bony ingrowth occurring 3-4 weeks postoperatively. There was significant difference between the trend of healing for defects receiving 0.1g of ACBG and those receiving 0.3g and 0.75g of ACBG.Histomorphometric data analysis showed there was no significant difference between area fractions of total bone, lamellar bone, or woven bone between grafted defects and nongrafted defects 8 weeks after ACBG transplantation. There was also no significant difference in area fraction values of total bone, lamellar bone, or woven bone between defects treated with 0.1g of ACBG and defects treated with 0.75g of ACBG, 8 weeks postoperatively. (Abstract shortened by UMI.).Source: Masters Abstracts International, Volume: 31-02, page: 0722