International audienceThe motion of a spherical particle (with radius 1 to 6 mm) in a viscous fluid is measured using laser interferometry. The typical sensitivity on the measured displacement of the sphere is of the order of 50 nm. The particle is moving on the axis of a closed cylinder. The hydrodynamic interactions between the particle and the walls of the cylinder are compared with the theoretical result of Sano [J. Phys. Soc. Jpn. 56, 2713 (1987)] valid for a very small sphere. The agreement is excellent for the smallest sphere used in the experiment. The experiment also agrees with the result from the theory of lubrication when the sphere is close to a plane end wall. The effect of the particle roughness appears at small distances. La...