FSI simulation of CSF hydrodynamic changes in a large population of non-communicating hydrocephalus patients during treatment process with regard to their clinical symptoms - Fig 2

<p>(a) and (b) show the three grid sizes used in the mesh independence study for maximum CSF pressure and maximum CSF velocity in aqueduct of Sylvius and upper convexity of the subarachnoid space for NCH patient No.1 before shunting, respectively. (c) shows the comparison of the maximum CSF velocities measured by cine-PC MRI in aqueduct of Sylvius and the maximum CSF velocities in aqueduct of Sylvius calculated by the FSI simulation for all 13 normal subjects and 11 patients. (d) shows the comparison of the cine-PC MRI velocity diagram in aqueduct of Sylvius and the velocity diagram calculated by the FSI simulation for the normal subject No. 2 and NCH patient No.1 before shunting. It is worth mentioning that the NCH patient No.1 before shunting and normal subject No. 2 have the highest velocity. (e) shows the comparison of the maximum ICP measured by ICP monitoring and the maximum ICP calculated by the FSI simulation for all 11 patients before shunting. SAS: subarachnoid space; AS: aqueduct of Sylvius; CSF: cerebrospinal fluid; NS: normal subject; NCH: non-communicating hydrocephalus; ICP: intracranial pressure.