Alignment of antigenic residues in VP4 between the strains contained in Rotarix^TM and RotaTeq^TM and Pakistani P[8] and P[4].

<p><b>(A)</b> Antigenic residues are divided in three antigenic epitopes in VP8* (8–1, 8–2, 8–3 and 8–4). Amino acids in green are different from both Rotarix^TM and G3 strain of RotaTeq^TM. <b>(B)</b> Surface representation of the VP8* core (PDB 1KQR). Antigenic epitopes are colored red 8–1, orange 8–2, green 8–3 and blue 8–4. Surface exposed residues that differ between Pakistani G3P[8] and vaccine Rotarix^TM and RotaTeq^TM are shown in cyan.