Additional file 1: of Large inter- and intra-case variability of first generation tau PET ligand binding in neurodegenerative dementias

Table S1. Extended demographic data of cases included in the study. Figure S1. Tau immunohistochemistry in cases with primary tauopathies. Figure S2. Lack of fluorescent tau tracer binding in cases with primary tauopathies. Figure S3. Lack of tau tracer binding to the medial temporal lobe of control cases CTRL1–CTRL4 with and without tau pathology. Figure S4. Representative immunofluorescence images showing AT8 immunoreactive tau inclusions depicted by fluorescent tau tracers. Figure S5. Concomitant labelling of tissue from Alzheimer’s disease cases with fluorescent tau tracers and phospho-tau specific antibodies. Figure S6. Quantitative phosphorimaging with [18F]THK-5117. (PDF 2092 kb