Metal cofactor modulated folding and target recognition of HIV-1 NCp7 - Fig 5

<p>(<b>A</b>) Probabilities of the two different folding mechanisms of ZF1(red) and ZF2(blue) at different Zn²⁺ concentrations. The squares represent the “binding induced folding” pathway, whereas the circles represent the “conformational selection” pathway. (<b>B</b>) Represent folding trajectories of ZF1 with “binding induced folding”mechanism (blue) and “conformational selection” mechanism (red), projected onto the space formed by the binding energy and <i>Q</i> value. (<b>C</b>) The mean first passage time(MFPT) of the folding of NCp7(red), ZF1(blue) and ZF2(green) as a function of Zn²⁺ concentrations.