Oxycodone hydrochloride immediate-release analgesic for managing severe pain: abuse-deterrent formulations

AH Kibbe,1 TS Franko,2 VM Shah2 1Department of Pharmaceutical Sciences, Nesbitt School of Pharmacy, Wilkes University, Wilkes-Barre, PA, USA; 2Department of Clinical Pharmacy, Nesbitt School of Pharmacy, Wilkes University, Wilkes-Barre, PA, USA Abstract: This paper is an expert opinion in response to the development of abuse-deterrent immediate-release tablets containing oxycodone HCl. There is a potential impact, both positive and negative, of this type of dosage form on patients, those suffering from the disease of addiction, health care providers, and the cost of health care. Keywords: non-metabolizable polymer, opioids, risk/benefit, IV abuse, nasal abus