Three-dimensional OCT based Guinea pig eye model: Relating morphology and optics

12 pags., 6 figs., 3 tabs. -- OCIS codes: (110.4500) Optical coherence tomography, (110.6880) Three-dimensional image acquisition, (100.2960) Image analysis, (330.7327) Visual optics, ophthalmic instrumentation, (330.7324) Visual optics, comparative animal models, (330.5370) Physiological opticsCustom Spectral Optical Coherence Tomography (SOCT) provided with automatic quantification and distortion correction algorithms was used to measure the 3-D morphology in guinea pig eyes (n = 8, 30 days; n = 5, 40 days). Animals were measured awake in vivo under cyclopegia. Measurements showed low intraocular variability (<4% in corneal and anterior lens radii and <8% in the posterior lens radii,