Differential T cell signaling pathway activation by tacrolimus and belatacept after kidney transplantation

Monitoring Intra-cellular Tacrolimus Concentrations in Solid Organ Transplantation: Use of Peripheral Blood Mononuclear Cells and Graft Biopsy Tissue

Benedetta C. Sallustio
Benedetta C. Sallustio

October 2021

Tacrolimus is an essential immunosuppressant for the prevention of rejection in solid organ transpla...

Monitoring of gene expression in tacrolimus-treated de novo renal allograft recipients facilitates individualized immunosuppression : results of the IMAGEN study

Sommerer, C.
Brunet, M.
Budde, K.
Millán, O.
Guirado, Luis
Glander, P.
Meuer, S.
Zeier, M.
Giese, Thomas

January 2021

Aims: Calcineurin inhibitors (CNI) have a small therapeutic window, and drug monitoring is required....

Progress in tacrolimus monitoring in organ transplantation : a multidisciplinary approach

Capron, Arnaud

January 2010

Tacrolimus (Tac), a macrolide lactone produced by the fungus Streptomyces tsukubaensis, is nowadays ...

Differential T cell signaling pathway activation by tacrolimus and belatacept after kidney transplantation: Post Hoc analysis of a randomised-controlled trial

Kannegieter, Nynke
Hesselink, Dennis
Dieterich, Marjolein
Graav, Gretchen
Kraaijeveld, Rens
Baan, Carla

December 2017

Pharmacokinetic immunosuppressive drug monitoring poorly correlates with clinical outcomes after sol...

Monitoring Signal Transduction after Kidney Transplantation

Kannegieter, Nynke

May 2018

The introduction of calcineurin inhibitors (CNIs) and mycophenolic acid (MPA) to the transplantation...

Pharmacodynamic Monitoring of Tacrolimus-based Immunosuppression in CD14+ Monocytes after Kidney Transplantation

Kannegieter, N.M. (Nynke)
Hesselink, D.A. (Dennis)
Dieterich, M. (Marjolein)
Graav, G.N. (Gretchen) de
Kraaijeveld, R. (Rens)
Rowshani, A.T. (Ajda)
Leenen, P.J.M. (Pieter)
Baan, C.C. (Carla)

June 2017

Background: Monocytes significantly contribute to ischemia-reperfusion injury and allograft rejectio...

Analysis of NFATc1 amplification in T cells for pharmacodynamic monitoring of tacrolimus in kidney transplant recipients

Kannegieter, N.M. (Nynke)
Hesselink, D.A. (Dennis)
Dieterich, M. (Marjolein)
Graav, G.N. (Gretchen) de
Kraaijeveld, R. (Rens)
Baan, C.C. (Carla)

July 2018

Background Therapeutic drug monitoring (TDM) of tacrolimus, based on blood concentrations, shows an ...

Pharmacokinetic considerations related to therapeutic drug monitoring of tacrolimus in kidney transplant patients

Andrews, L.M. (Louise)
Li, Y. (Yi)
Winter, B.C.M. (Brenda) de
Shi, Y.Y. (Yunjing)
Baan, C.C. (Carla)
Gelder, T. (Teun) van
Hesselink, D.A. (Dennis)

December 2017

Introduction: Tacrolimus (Tac) is the cornerstone of immunosuppressive therapy after solid organ tra...

Phospho-specific flow cytometry for pharmacodynamic monitoring of immunosuppressive therapy in transplantation

Baan, C.C. (Carla)
Bouvy, A.P. (Anne)
Vafadari, R. (Ramin)
Weimar, W. (Willem)

November 2012

Organ transplant recipients frequently suffer from toxicity or from lack of efficacy of immunosuppre...

Immunomonitoring of Tacrolimus in Healthy Volunteers: The First Step from PK- to PD-Based Therapeutic Drug Monitoring?

In 't Veld, A.E. (Aliede E.)
Grievink, H.W. (Hendrika W.)
Saghari, M. (Mahdi)
Stuurman, F.E. (Frederik E.)
Kam, M. (Marieke) de
de Vries, A.P.J. (Aiko P J)
Winter, B.C.M. (Brenda) de
Burggraaf, J. (Jacobus)
Cohen, A.F.
Moerland, M. (Matthijs)

September 2019

Therapeutic drug monitoring is routinely performed to maintain optimal tacrolimus concentrations in ...

Analysis of NFATc1 amplification in T cells for pharmacodynamic monitoring of tacrolimus in kidney transplant recipients.

Nynke M Kannegieter
Dennis A Hesselink
Marjolein Dieterich
Gretchen N de Graav
Rens Kraaijeveld
Carla C Baan

January 2018

BACKGROUND:Therapeutic drug monitoring (TDM) of tacrolimus, based on blood concentrations, shows an ...

Monitoring intracellular tacrolimus concentrations and its relationship with rejection in the early phase after renal transplantation

Francke, M.I.
Andrews, L.M.
, H.L. le
Velde, D. van de
Dieterich, M.
Udomkarnjananun, S.
Clahsen-van Groningen, M.C.
Baan, C.C.
Gelder, T. van
Winter, B.C.M. de
Hesselink, D.A.

March 2022

Introduction: After kidney transplantation, rejection and drug-related toxicity occur despite tacrol...

Cytotoxicity and T-B Cell Crosstalk in Belatacept-Treated Kidney Transplant Patients

Graav, G.N. (Gretchen) de

April 2017

In this dissertation, we aimed to learn more about the immune mechanisms involved in alloreactivity ...

Monitoring the tacrolimus concentration in peripheral blood mononuclear cells of kidney transplant recipients

Francke, Marith I.
Hesselink, Dennis A.
Li, Yi
Koch, Birgit C.P.
de Wit, Lucia E.A.
van Schaik, Ron H.N.
Yang, Lin
Baan, Carla C.
van Gelder, Teun
de Winter, Brenda C.M.

April 2021

Aims: Tacrolimus is a critical dose drug and to avoid under- and overexposure, therapeutic drug moni...

Biochemical monitoring of mTOR inhibitor-based immunosuppression following kidney transplantation: A novel approach for tailored immunosuppressive therapy

Hartmann, Bertram
Schmid, Gerald
Graeb, Christian
Bruns, Christiane J.
Fischereder, Michael
Jauch, Karl-Walter
Heeschen, Christopher
Guba, Markus

December 2005

Biochemical monitoring of mTOR inhibitor-based immunosuppression following kidney transplantation: A...

Monitoring Intra-cellular Tacrolimus Concentrations in Solid Organ Transplantation: Use of Peripheral Blood Mononuclear Cells and Graft Biopsy Tissue

Benedetta C. Sallustio
Benedetta C. Sallustio

October 2021

Tacrolimus is an essential immunosuppressant for the prevention of rejection in solid organ transpla...

Monitoring of gene expression in tacrolimus-treated de novo renal allograft recipients facilitates individualized immunosuppression : results of the IMAGEN study

Sommerer, C.
Brunet, M.
Budde, K.
Millán, O.
Guirado, Luis
Glander, P.
Meuer, S.
Zeier, M.
Giese, Thomas

January 2021

Aims: Calcineurin inhibitors (CNI) have a small therapeutic window, and drug monitoring is required....

Progress in tacrolimus monitoring in organ transplantation : a multidisciplinary approach

Capron, Arnaud

January 2010

Tacrolimus (Tac), a macrolide lactone produced by the fungus Streptomyces tsukubaensis, is nowadays ...

Differential T cell signaling pathway activation by tacrolimus and belatacept after kidney transplantation: Post Hoc analysis of a randomised-controlled trial

Kannegieter, Nynke
Hesselink, Dennis
Dieterich, Marjolein
Graav, Gretchen
Kraaijeveld, Rens
Baan, Carla

December 2017

Pharmacokinetic immunosuppressive drug monitoring poorly correlates with clinical outcomes after sol...

Monitoring Signal Transduction after Kidney Transplantation

Kannegieter, Nynke

May 2018

The introduction of calcineurin inhibitors (CNIs) and mycophenolic acid (MPA) to the transplantation...

Pharmacodynamic Monitoring of Tacrolimus-based Immunosuppression in CD14+ Monocytes after Kidney Transplantation

Kannegieter, N.M. (Nynke)
Hesselink, D.A. (Dennis)
Dieterich, M. (Marjolein)
Graav, G.N. (Gretchen) de
Kraaijeveld, R. (Rens)
Rowshani, A.T. (Ajda)
Leenen, P.J.M. (Pieter)
Baan, C.C. (Carla)

June 2017

Background: Monocytes significantly contribute to ischemia-reperfusion injury and allograft rejectio...

Analysis of NFATc1 amplification in T cells for pharmacodynamic monitoring of tacrolimus in kidney transplant recipients

Kannegieter, N.M. (Nynke)
Hesselink, D.A. (Dennis)
Dieterich, M. (Marjolein)
Graav, G.N. (Gretchen) de
Kraaijeveld, R. (Rens)
Baan, C.C. (Carla)

July 2018

Background Therapeutic drug monitoring (TDM) of tacrolimus, based on blood concentrations, shows an ...

Pharmacokinetic considerations related to therapeutic drug monitoring of tacrolimus in kidney transplant patients

Andrews, L.M. (Louise)
Li, Y. (Yi)
Winter, B.C.M. (Brenda) de
Shi, Y.Y. (Yunjing)
Baan, C.C. (Carla)
Gelder, T. (Teun) van
Hesselink, D.A. (Dennis)

December 2017

Introduction: Tacrolimus (Tac) is the cornerstone of immunosuppressive therapy after solid organ tra...

Phospho-specific flow cytometry for pharmacodynamic monitoring of immunosuppressive therapy in transplantation

Baan, C.C. (Carla)
Bouvy, A.P. (Anne)
Vafadari, R. (Ramin)
Weimar, W. (Willem)

November 2012

Organ transplant recipients frequently suffer from toxicity or from lack of efficacy of immunosuppre...

Immunomonitoring of Tacrolimus in Healthy Volunteers: The First Step from PK- to PD-Based Therapeutic Drug Monitoring?

In 't Veld, A.E. (Aliede E.)
Grievink, H.W. (Hendrika W.)
Saghari, M. (Mahdi)
Stuurman, F.E. (Frederik E.)
Kam, M. (Marieke) de
de Vries, A.P.J. (Aiko P J)
Winter, B.C.M. (Brenda) de
Burggraaf, J. (Jacobus)
Cohen, A.F.
Moerland, M. (Matthijs)

September 2019

Therapeutic drug monitoring is routinely performed to maintain optimal tacrolimus concentrations in ...

Analysis of NFATc1 amplification in T cells for pharmacodynamic monitoring of tacrolimus in kidney transplant recipients.

Nynke M Kannegieter
Dennis A Hesselink
Marjolein Dieterich
Gretchen N de Graav
Rens Kraaijeveld
Carla C Baan

January 2018

BACKGROUND:Therapeutic drug monitoring (TDM) of tacrolimus, based on blood concentrations, shows an ...

Monitoring intracellular tacrolimus concentrations and its relationship with rejection in the early phase after renal transplantation

Francke, M.I.
Andrews, L.M.
, H.L. le
Velde, D. van de
Dieterich, M.
Udomkarnjananun, S.
Clahsen-van Groningen, M.C.
Baan, C.C.
Gelder, T. van
Winter, B.C.M. de
Hesselink, D.A.

March 2022

Introduction: After kidney transplantation, rejection and drug-related toxicity occur despite tacrol...

Cytotoxicity and T-B Cell Crosstalk in Belatacept-Treated Kidney Transplant Patients

Graav, G.N. (Gretchen) de

April 2017

In this dissertation, we aimed to learn more about the immune mechanisms involved in alloreactivity ...

Monitoring the tacrolimus concentration in peripheral blood mononuclear cells of kidney transplant recipients

Francke, Marith I.
Hesselink, Dennis A.
Li, Yi
Koch, Birgit C.P.
de Wit, Lucia E.A.
van Schaik, Ron H.N.
Yang, Lin
Baan, Carla C.
van Gelder, Teun
de Winter, Brenda C.M.

April 2021

Aims: Tacrolimus is a critical dose drug and to avoid under- and overexposure, therapeutic drug moni...

Biochemical monitoring of mTOR inhibitor-based immunosuppression following kidney transplantation: A novel approach for tailored immunosuppressive therapy

Hartmann, Bertram
Schmid, Gerald
Graeb, Christian
Bruns, Christiane J.
Fischereder, Michael
Jauch, Karl-Walter
Heeschen, Christopher
Guba, Markus

December 2005

Biochemical monitoring of mTOR inhibitor-based immunosuppression following kidney transplantation: A...

Monitoring Intra-cellular Tacrolimus Concentrations in Solid Organ Transplantation: Use of Peripheral Blood Mononuclear Cells and Graft Biopsy Tissue

Benedetta C. Sallustio
Benedetta C. Sallustio

October 2021

Tacrolimus is an essential immunosuppressant for the prevention of rejection in solid organ transpla...

Monitoring of gene expression in tacrolimus-treated de novo renal allograft recipients facilitates individualized immunosuppression : results of the IMAGEN study

Sommerer, C.
Brunet, M.
Budde, K.
Millán, O.
Guirado, Luis
Glander, P.
Meuer, S.
Zeier, M.
Giese, Thomas

January 2021

Aims: Calcineurin inhibitors (CNI) have a small therapeutic window, and drug monitoring is required....

Progress in tacrolimus monitoring in organ transplantation : a multidisciplinary approach

Capron, Arnaud

January 2010

Tacrolimus (Tac), a macrolide lactone produced by the fungus Streptomyces tsukubaensis, is nowadays ...

Differential T cell signaling pathway activation by tacrolimus and belatacept after kidney transplantation

Abstract

Extracted data

Differential T cell signaling pathway activation by tacrolimus and belatacept after kidney transplantation

Abstract

Extracted data

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