Rapid amino acid quantitation with pre-column derivatization; ultra-performance reverse phase liquid chromatography and single quadrupole mass spectrometry
- Pretorius, Carel J.
- McWhinney, Brett C.
- Sipinkoski, Bilyana
- Wilce, Alice
- Cox, David
- McWhinney, Avis
- Ungerer, Jacobus P. J.
Publication date
December 2017
DOI Publisher
Elsevier BV ISSN
0009-8981 Citation count (estimate)
1Abstract
Background: We optimized a quantitative amino acid method with pre-column derivatization, norvaline (nva) internal standard and reverse phase ultra-performance liquid chromatography by replacing the ultraviolet detector with a single quadrupole mass spectrometer (MSnva)
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