Topical Treatment of Skin Cancers and the Risks of ‘Fighting Fire with Fire’

While surgical excision remains the mainstay of managing non-melanoma skin cancers, many authors have published successful topical or non-surgical options for treating non-melanoma skin cancers [1]. A recent review article compared the efficacy of topical 5-fluorouracil (5FU), topical imiquimod 5 % cream, intralesional 5FU, intralesional methotrexate (MTX), intralesional bleomycin, and intralesional interferon (IFN) for non-melanoma skin cancers