Add to ORKGA small library of organic compounds that had been synthesized in-house was evaluated for possible antiproliferative activity. The assessment of antiproliferative activity of the pyrazole scaffold has directed the synthesis on structural analogues of previous pyrazole derivatives
Equipe : Synthèse de Molécules d'Intérêt Thérapeutique (SMITH)International audiencePyrazolo[1,5-a]-...
Pyrazole moiety represents an important category of heterocyclic compound in pharmaceutical and medi...
Pyrazole moiety is one of the main scaffold for many anticancer drug candidates.Many pyrazole deriva...
A series of highly functionalized pyrazole derivatives has been prepared by a one-pot, versatile and...
International audienceTwo series of compounds carrying 3-amino-1,2,4-triazole scaffold were synthesi...
New pyrazole derivatives were designed and synthesized as potential protein kinase inhibitors in the...
As heterocyclic compounds show good biological activity, we have synthesized nitrogen containing com...
A series of pyrazolo-triazole hybrids were designed and synthesized by combining the 1,3-diphenyl py...
A series of 5-aryl-3-cyanomethylpyrazoles have been synthesized by refluxing 6-aryl-3-cyano-4-methyl...
A series of novel pyrazole and triazole derivatives containing 5-phenyl-2-furan functionality were d...
Based on a previously prepared lead compound, a new series of hybrid compounds was prepared and test...
Pyrazole, which is a five-membered heterocyclic ring containing two adjacent nitrogen, can be found ...
Anticancer screening of several 1,2,3-triazoles with heterocyclic fragments has been performed. The ...
Exploring the pharmacologically important pyrazolo[1,5-a][1,3,5]triazin-7(6H)-one scaffold for the c...
Several triazenoindazoles and triazenopyrazoles were prepared transforming the appropriate aminoinda...
Equipe : Synthèse de Molécules d'Intérêt Thérapeutique (SMITH)International audiencePyrazolo[1,5-a]-...
Pyrazole moiety represents an important category of heterocyclic compound in pharmaceutical and medi...
Pyrazole moiety is one of the main scaffold for many anticancer drug candidates.Many pyrazole deriva...
A series of highly functionalized pyrazole derivatives has been prepared by a one-pot, versatile and...
International audienceTwo series of compounds carrying 3-amino-1,2,4-triazole scaffold were synthesi...
New pyrazole derivatives were designed and synthesized as potential protein kinase inhibitors in the...
As heterocyclic compounds show good biological activity, we have synthesized nitrogen containing com...
A series of pyrazolo-triazole hybrids were designed and synthesized by combining the 1,3-diphenyl py...
A series of 5-aryl-3-cyanomethylpyrazoles have been synthesized by refluxing 6-aryl-3-cyano-4-methyl...
A series of novel pyrazole and triazole derivatives containing 5-phenyl-2-furan functionality were d...
Based on a previously prepared lead compound, a new series of hybrid compounds was prepared and test...
Pyrazole, which is a five-membered heterocyclic ring containing two adjacent nitrogen, can be found ...
Anticancer screening of several 1,2,3-triazoles with heterocyclic fragments has been performed. The ...
Exploring the pharmacologically important pyrazolo[1,5-a][1,3,5]triazin-7(6H)-one scaffold for the c...
Several triazenoindazoles and triazenopyrazoles were prepared transforming the appropriate aminoinda...
Equipe : Synthèse de Molécules d'Intérêt Thérapeutique (SMITH)International audiencePyrazolo[1,5-a]-...
Pyrazole moiety represents an important category of heterocyclic compound in pharmaceutical and medi...
Pyrazole moiety is one of the main scaffold for many anticancer drug candidates.Many pyrazole deriva...