<p>(A) Gating strategies. (B) FC plots of FL-HA binding versus CD44 expression by BM LSK, CLP, GMP, CD150<sup>+</sup> LSK, CD150<sup>-</sup> LSK, LT-HSC, ST-HSC and MPP from CD44<sup>+/+</sup> naïve mice. (C) Percentage of FL-HA binding by BM LSK, CLP, GMP, CD150<sup>+</sup> LSK, and CD150<sup>-</sup> LSK. (D) Percentage of FL-HA binding by CD150<sup>+</sup> LSK and CD150<sup>-</sup> LSK populations from the same mice as (C). (E) Percentage of FL-HA binding by BM LT-HSC, ST-HSC and MPP. Mean +/- SD from at least six biological replicates of two independent experiments. **p<0.01, ***p<0.001 calculated by Student’s t-test.</p
<p>Bone marrow from Rosa26-tdRFP<sup>+</sup>;Pf4-Cre<sup>+</sup> and litter matched control mice was...
<p>(A) Purified SP4 thymocytes, and CD4<sup>+</sup> naïve T cells from lymph nodes of C57BL/6 mice w...
<p>(A) Genomic structure of mouse Cd44 is shown. Cd44 has 9 non-variable exons numbered 1 to 9 (larg...
<p>(A) Cell cycle analysis of BM LSK cells with 7AAD labeling. Histograms showing 7AAD labeling of H...
<p>(A) Gating strategies for Lineage<sup>-</sup> BM, LSK, and CD150. (B-C) Percentage of WT-CD44 and...
<p>(A) Gating strategy. After lymphocytes gating based on forward-scatter (FSC) and side-scatter (SS...
<p>CD44<sup>-/-</sup> BMC were isolated from the femurs and tibia of mice that had received 5-FU 4 d...
<p>(A) HA binding of CD45<sup>+</sup> cells from a representative SD fed B6, <i>Ccr2<sup>−/−</sup></...
<p>(A) Plots depict CD44 and CD62L expression on splenic <i>Hdac1<sup>f/f</sup></i> and <i>Hdac1<sup...
<p>(<b>A</b>) LSK from control and Tg mice were resolved with CD150, CD48, Flk2 and CD34 staining in...
<p>(<b>A, B</b>) LSK were gated with c-kit and Sca-1 in BM (<b>A</b>) and spleen (<b>B</b>). The per...
<p>(a) CD117 and CD133 staining of tumor cells. Mice salivary gland tumor cells were divided into CD...
<p>(A) Binding of HA by liver leukocytes of LD fed B6 and <i>Ccr2<sup>−/−</sup></i> mice. (A) Propor...
<p>Lethally irradiated CD45.1 mice were reconstituted with 2 x 10<sup>5</sup> BMC containing an equa...
<p>(<b>A</b>) LSK were resolved with CD150 and CD34. CD34<sup>−</sup> CD150<sup>Hi</sup>, <sup>Lo</s...
<p>Bone marrow from Rosa26-tdRFP<sup>+</sup>;Pf4-Cre<sup>+</sup> and litter matched control mice was...
<p>(A) Purified SP4 thymocytes, and CD4<sup>+</sup> naïve T cells from lymph nodes of C57BL/6 mice w...
<p>(A) Genomic structure of mouse Cd44 is shown. Cd44 has 9 non-variable exons numbered 1 to 9 (larg...
<p>(A) Cell cycle analysis of BM LSK cells with 7AAD labeling. Histograms showing 7AAD labeling of H...
<p>(A) Gating strategies for Lineage<sup>-</sup> BM, LSK, and CD150. (B-C) Percentage of WT-CD44 and...
<p>(A) Gating strategy. After lymphocytes gating based on forward-scatter (FSC) and side-scatter (SS...
<p>CD44<sup>-/-</sup> BMC were isolated from the femurs and tibia of mice that had received 5-FU 4 d...
<p>(A) HA binding of CD45<sup>+</sup> cells from a representative SD fed B6, <i>Ccr2<sup>−/−</sup></...
<p>(A) Plots depict CD44 and CD62L expression on splenic <i>Hdac1<sup>f/f</sup></i> and <i>Hdac1<sup...
<p>(<b>A</b>) LSK from control and Tg mice were resolved with CD150, CD48, Flk2 and CD34 staining in...
<p>(<b>A, B</b>) LSK were gated with c-kit and Sca-1 in BM (<b>A</b>) and spleen (<b>B</b>). The per...
<p>(a) CD117 and CD133 staining of tumor cells. Mice salivary gland tumor cells were divided into CD...
<p>(A) Binding of HA by liver leukocytes of LD fed B6 and <i>Ccr2<sup>−/−</sup></i> mice. (A) Propor...
<p>Lethally irradiated CD45.1 mice were reconstituted with 2 x 10<sup>5</sup> BMC containing an equa...
<p>(<b>A</b>) LSK were resolved with CD150 and CD34. CD34<sup>−</sup> CD150<sup>Hi</sup>, <sup>Lo</s...
<p>Bone marrow from Rosa26-tdRFP<sup>+</sup>;Pf4-Cre<sup>+</sup> and litter matched control mice was...
<p>(A) Purified SP4 thymocytes, and CD4<sup>+</sup> naïve T cells from lymph nodes of C57BL/6 mice w...
<p>(A) Genomic structure of mouse Cd44 is shown. Cd44 has 9 non-variable exons numbered 1 to 9 (larg...