HSV-2 infection dynamics from a single model simulation.

<p>(A) Total (summed across the whole simulation region) HSV-2 and infected epithelial cell counts. (B) Cytokine concentration. (C) CD4+ and CD8+ T cell densities. (D) Percentage of the modelled region damaged due to lesion development. The time at which each tracked value peaks during a HSV-2 outbreak is indicated to highlight the delay in immune cell response and tissue damage.