Surface plasmon resonance (SPR) has been used to determine apparent stability constants for the non-covalent interactions of cyclodextrin (CD) hosts with small organic guests. This technique allows detection of the molecular interactions by monitoring changes in refractive index at gold surfaces on which the guests are immobilized. The magnitude of an SPR response is proportional to the mass change at a surface, and thus the technique has most commonly been used in the past to study large molecules such as proteins and DNA. Now SPR has been employed to study the interactions of αCD, βCD, γCD, per-2,6-dimethyl-βCD and Molecusol™ (hydroxypropyl-βCD) with immobilized N-(1-adamantylmethyl)-, N-octyl-, N-benzyl-, N-(4-metliylbenzyl)-, N-(4-tert-...
Bio-molecular interactions exist ubiquitously in all biological systems. This dissertation project w...
Bio-molecular interactions exist ubiquitously in all biological systems. This dissertation project w...
The use of small molecules to interfere with protein-protein interactions has tremendous therapeutic...
Surface plasmon resonance (SPR) is one of the most important techniques for the detection and the ch...
Surface plasmon resonance (SPR) is one of the most important techniques for the detection and the ch...
The surface plasmon resonance (SPR) technique has been primarily used in the field of biology, in pa...
In this study, a Surface Plasmon Resonance (SPR) optical sensor, based on Kretschmann configuration...
With the introduction of new instruments and improved sensor chip chemistries, surface plasmon reson...
Recently, the observation of pH-induced conformational changes of biomolecules supported on carboxym...
In the present paper we describe a simple method to immobilize amino cyclodextrins (CDs) and methyla...
In the present paper we describe a simple method to immobilize amino cyclodextrins (CDs) and methyla...
The kinetic of the assembly and adsorption processes of mono(6-deoxy-6-mercapto)-beta-cyclodextrin (...
In the recent years, surface plasmon resonance (SPR) has become one of the major methods for studyin...
Surface Plasmon Resonance (SPR) is a quantitative, label-free method for determining molecular inter...
This thesis explores the applicability of surface plasmon resonance (SPR) with the aim to improve an...
Bio-molecular interactions exist ubiquitously in all biological systems. This dissertation project w...
Bio-molecular interactions exist ubiquitously in all biological systems. This dissertation project w...
The use of small molecules to interfere with protein-protein interactions has tremendous therapeutic...
Surface plasmon resonance (SPR) is one of the most important techniques for the detection and the ch...
Surface plasmon resonance (SPR) is one of the most important techniques for the detection and the ch...
The surface plasmon resonance (SPR) technique has been primarily used in the field of biology, in pa...
In this study, a Surface Plasmon Resonance (SPR) optical sensor, based on Kretschmann configuration...
With the introduction of new instruments and improved sensor chip chemistries, surface plasmon reson...
Recently, the observation of pH-induced conformational changes of biomolecules supported on carboxym...
In the present paper we describe a simple method to immobilize amino cyclodextrins (CDs) and methyla...
In the present paper we describe a simple method to immobilize amino cyclodextrins (CDs) and methyla...
The kinetic of the assembly and adsorption processes of mono(6-deoxy-6-mercapto)-beta-cyclodextrin (...
In the recent years, surface plasmon resonance (SPR) has become one of the major methods for studyin...
Surface Plasmon Resonance (SPR) is a quantitative, label-free method for determining molecular inter...
This thesis explores the applicability of surface plasmon resonance (SPR) with the aim to improve an...
Bio-molecular interactions exist ubiquitously in all biological systems. This dissertation project w...
Bio-molecular interactions exist ubiquitously in all biological systems. This dissertation project w...
The use of small molecules to interfere with protein-protein interactions has tremendous therapeutic...