Pioglitazone acutely reduces energy metabolism and insulin secretion in rats
- Lamontagne, Julien
- Jalbert-Arsenault, Élise
- Pepin, Emilie
- Peyot, Marie-Line
- Ruderman, Neil
- Nolan, Christopher
- Joly, Erik
- Madiraju, Murthy S R
- Poitout, Vincent
- Prentki, Marc
Publication date
February 2016
DOI Publisher
American Diabetes Association Journal
DiabetesAbstract
Our objective was to determine if the insulin-sensitizing drug pioglitazone acutely reduces insulin secretion and causes metabolic deceleration in vivo independently of change in insulin sensitivity. We assessed glucose homeostasis by hyperinsulinemiceug
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