Kinetics of the Biotransformation of Maleylacetone and Chlorofluoroacetic Acid by Polymorphic Variants of Human Glutathione Transferase Zeta (hGSTZ1-1)
- Lantum, Hoffman
- Board, Philip
- Anders, Michael
Publication date
December 2015
DOI Publisher
American Chemical Society (ACS) ISSN
0893-228X Journal
Chemical Research in Toxicology Citation count (estimate)
7Abstract
Glutathione transferase zeta (GSTZ1-1) catalyzes the cis-trans isomerization of maleylacetoacetate and the biotransformation of a range of α-haloacids. The objective of this study was to determine the kinetics of the biotransformation of maleylacetone (
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