How are biological structures maintained in a cellular environment that constantly threatens protein integrity? Here we elucidate proteostasis mechanisms affecting the Z disk, a protein assembly essential for actin anchoring in striated muscles, which i
Metabolic homeostasis is essential for cellular survival and proper tissue function. Multi-systemic ...
SummaryThe ubiquitin-proteasome and autophagy-lysosome pathways are the two major routes for protein...
Autophagy is an essential cellular process for protein and organelle quality control. Analyses of pr...
Autophagy is an evolutionarily conserved intracellular system that selectively eliminates protein ag...
SummaryMechanical tension is an ever-present physiological stimulus essential for the development an...
This review assesses the importance of proteostasis in skeletal muscle maintenance with a specific e...
Abstract Muscle atrophy derived from excessive proteolysis is a hallmark of numerous d...
Protein folding factors (chaperones) are required for many diverse cellular functions. In striated m...
AbstractMuscle mass represents 40–50% of the human body and, in mammals, is one of the most importan...
Autophagy is a catabolic process that facilitates degradation of intracellular components in lysosom...
Muscle mass represents 40-50% of the human body and, in mammals, is one of the most important sites ...
Skeletal muscles are the agent of motion and one of the most important tissues responsible for the c...
Skeletal muscles are the agent of motion and one of the most important tissues responsible for the c...
International audienceFor long-lived contractile cells, such as striated muscle cells, maintaining p...
Autophagy has been implicated as a major factor in the development of a number of diseases of skelet...
Metabolic homeostasis is essential for cellular survival and proper tissue function. Multi-systemic ...
SummaryThe ubiquitin-proteasome and autophagy-lysosome pathways are the two major routes for protein...
Autophagy is an essential cellular process for protein and organelle quality control. Analyses of pr...
Autophagy is an evolutionarily conserved intracellular system that selectively eliminates protein ag...
SummaryMechanical tension is an ever-present physiological stimulus essential for the development an...
This review assesses the importance of proteostasis in skeletal muscle maintenance with a specific e...
Abstract Muscle atrophy derived from excessive proteolysis is a hallmark of numerous d...
Protein folding factors (chaperones) are required for many diverse cellular functions. In striated m...
AbstractMuscle mass represents 40–50% of the human body and, in mammals, is one of the most importan...
Autophagy is a catabolic process that facilitates degradation of intracellular components in lysosom...
Muscle mass represents 40-50% of the human body and, in mammals, is one of the most important sites ...
Skeletal muscles are the agent of motion and one of the most important tissues responsible for the c...
Skeletal muscles are the agent of motion and one of the most important tissues responsible for the c...
International audienceFor long-lived contractile cells, such as striated muscle cells, maintaining p...
Autophagy has been implicated as a major factor in the development of a number of diseases of skelet...
Metabolic homeostasis is essential for cellular survival and proper tissue function. Multi-systemic ...
SummaryThe ubiquitin-proteasome and autophagy-lysosome pathways are the two major routes for protein...
Autophagy is an essential cellular process for protein and organelle quality control. Analyses of pr...