Selective modulation of different GABA(A) receptor isoforms by diazepam and etomidate in hippocampal neurons

Current potentiation by diazepam but not GABA sensitivity is determined by a single histidine residue

Kleingoor, C.
Wieland, H.
Korpi, E.
Seeburg, P.
Kettenmann, H.

February 1993

AB THE GABAA/benzodiazepine receptor is the principal inhibitory neurotransmitter receptor in the ma...

Conductance of recombinant GABA(A) channels is increased in cells co-expressing GABA(A) receptor-associated protein

Everitt, AB
Luu, T
Cromer, B
Tierney, ML
Birnir, Bryndis
Olsen, RW
Gage, PW

January 2004

High conductance gamma- aminobutyric acid type A ( GABA(A)) channels (> 40 picosiemens ( pS)) have b...

Current potentiation by diazepam but not GABA sensitivity is determined by a single histidine residue

Kleingoor, C.
Wieland, H.
Korpi, E.R.
Seeburg, P.H.
Kettenmann, H.

February 1993

The GABAA/benzodiazepine receptor is the principal inhibitory neurotransmitter receptor in the mamma...

Selective modulation of different GABAA receptor isoforms by diazepam and etomidate in hippocampal neurons

Seymour, Victoria A. L.
Curmi, John P.
Howitt, Susan M.
Casarotto, Marco G.
Laver, Derek R.
Tierney, M. Louise

January 2012

Diazepam modulation of native γ2-containing GABAA (γGABAA) receptors increases...

Protein interactions involving the γ2 large cytoplasmic loop of GABAA receptors modulate conductance

Everitt, Andrea B.
Seymour, Victoria A. L.
Curmi, John
Laver, Derek R.
Gage, Peter W.
Tierney, M. Louise

January 2009

Native GABAA channels display a singlechannel conductance ranging between ~10 and 90 pS. Diazepam in...

Protein interactions involving the gamma2 large cytoplasmic loop of GABA A receptors modulate conductance

Everitt, Andrea
Seymour, Victoria
Curmi, John
Laver, Derek Rowland
Gage, Peter
Tierney, Mary (Louise)

February 2016

Native GABAA channels display a single-channel conductance ranging between ∼10 and 90 pS. Diazepam i...

Positive modulation of synaptic and extrasynaptic GABAA receptors by an antagonist of the high affinity benzodiazepine binding site.

Middendorp, Simon
Maldifassi, Maria Constanza
Baur, Roland
Sigel, Erwin

August 2015

GABAA receptors are the major inhibitory neurotransmitter receptors in the brain and are the target ...

Differential Drug Responses on Native GABAa Receptors Revealing Heterogeneity in Extrasynaptic Populations in Cultured Hippocampal Neurons

Seymour, Victoria
Everitt, Andrea
Tierney, Mary (Louise)

February 2016

Hippocampal pyramidal neurons potentially express multiple subtypes of GABAA receptors at extrasynap...

Relative positioning of classical benzodiazepines to the γ2-subunit of GABAA receptors.

Middendorp, Simon
Hurni, Evelyn
Schönberger, Matthias
Stein, Marco
Pangerl, Michael
Trauner, Dirk
Sigel, Erwin

August 2014

GABAA receptors are the major inhibitory neurotransmitter receptors in the brain. Benzodiazepine exe...

Extrasynaptic GABA(A) channels activated by THIP are modulated by diazepam in CA1 pyramidal neurons in the rat brain hippocampal slice

Lindquist, Catarina
Ebert, B
Birnir, Bryndis

January 2003

Single-channel currents were activated by THIP (4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol) in c...

Hippocampal GABA(A) channel conductance increased by diazepam

Eghbali, M
Curmi, J P
Birnir, Bryndis
Gage, P W

January 1997

Benzodiazepines, which are widely used clinically for relief of anxiety and for sedation, are though...

Relative Positioning of Classical Benzodiazepines to the γ2 Subunit of GABA-A Receptors

Middendorp, SJ
Hurni, E
Schönberger, Matthias
Stein, M
Pangerl, M
Trauner, D
Sigel, E

August 2014

GABAA receptors are the major inhibitory neurotransmitter receptors in the brain. Benzodiazepine exe...

Relative Positioning of Classical Benzodiazepines to the γ2 Subunit of GABA-A Receptors

Middendorp, S.J.
Hurni, E.
Schönberger, Matthias
Stein, M.
Pangerl, M.
Trauner, D.
Sigel, E.

August 2014

GABAA receptors are the major inhibitory neurotransmitter receptors in the brain. Benzodiazepine exe...

Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs

Baur, Roland
Tan, Kelly R
Lüscher, Benjamin P
Gonthier, Anne
Goeldner, Maurice
Sigel, Erwin

January 2008

Classical benzodiazepines, for example diazepam, interact with alpha(x)beta(2)gamma(2) GABA(A) recep...

Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs

Baur, Roland
Tan, Kelly R.
Lüscher, Benjamin P.
Gonthier, Anne
Goeldner, Maurice
Sigel, Erwin

January 2008

Classical benzodiazepines, for example diazepam, interact with alpha(x)beta(2)gamma(2) GABA(A) recep...

Current potentiation by diazepam but not GABA sensitivity is determined by a single histidine residue

Kleingoor, C.
Wieland, H.
Korpi, E.
Seeburg, P.
Kettenmann, H.

February 1993

AB THE GABAA/benzodiazepine receptor is the principal inhibitory neurotransmitter receptor in the ma...

Conductance of recombinant GABA(A) channels is increased in cells co-expressing GABA(A) receptor-associated protein

Everitt, AB
Luu, T
Cromer, B
Tierney, ML
Birnir, Bryndis
Olsen, RW
Gage, PW

January 2004

High conductance gamma- aminobutyric acid type A ( GABA(A)) channels (> 40 picosiemens ( pS)) have b...

Current potentiation by diazepam but not GABA sensitivity is determined by a single histidine residue

Kleingoor, C.
Wieland, H.
Korpi, E.R.
Seeburg, P.H.
Kettenmann, H.

February 1993

The GABAA/benzodiazepine receptor is the principal inhibitory neurotransmitter receptor in the mamma...

Selective modulation of different GABAA receptor isoforms by diazepam and etomidate in hippocampal neurons

Seymour, Victoria A. L.
Curmi, John P.
Howitt, Susan M.
Casarotto, Marco G.
Laver, Derek R.
Tierney, M. Louise

January 2012

Diazepam modulation of native γ2-containing GABAA (γGABAA) receptors increases...

Protein interactions involving the γ2 large cytoplasmic loop of GABAA receptors modulate conductance

Everitt, Andrea B.
Seymour, Victoria A. L.
Curmi, John
Laver, Derek R.
Gage, Peter W.
Tierney, M. Louise

January 2009

Native GABAA channels display a singlechannel conductance ranging between ~10 and 90 pS. Diazepam in...

Protein interactions involving the gamma2 large cytoplasmic loop of GABA A receptors modulate conductance

Everitt, Andrea
Seymour, Victoria
Curmi, John
Laver, Derek Rowland
Gage, Peter
Tierney, Mary (Louise)

February 2016

Native GABAA channels display a single-channel conductance ranging between ∼10 and 90 pS. Diazepam i...

Positive modulation of synaptic and extrasynaptic GABAA receptors by an antagonist of the high affinity benzodiazepine binding site.

Middendorp, Simon
Maldifassi, Maria Constanza
Baur, Roland
Sigel, Erwin

August 2015

GABAA receptors are the major inhibitory neurotransmitter receptors in the brain and are the target ...

Differential Drug Responses on Native GABAa Receptors Revealing Heterogeneity in Extrasynaptic Populations in Cultured Hippocampal Neurons

Seymour, Victoria
Everitt, Andrea
Tierney, Mary (Louise)

February 2016

Hippocampal pyramidal neurons potentially express multiple subtypes of GABAA receptors at extrasynap...

Relative positioning of classical benzodiazepines to the γ2-subunit of GABAA receptors.

Middendorp, Simon
Hurni, Evelyn
Schönberger, Matthias
Stein, Marco
Pangerl, Michael
Trauner, Dirk
Sigel, Erwin

August 2014

GABAA receptors are the major inhibitory neurotransmitter receptors in the brain. Benzodiazepine exe...

Extrasynaptic GABA(A) channels activated by THIP are modulated by diazepam in CA1 pyramidal neurons in the rat brain hippocampal slice

Lindquist, Catarina
Ebert, B
Birnir, Bryndis

January 2003

Single-channel currents were activated by THIP (4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol) in c...

Hippocampal GABA(A) channel conductance increased by diazepam

Eghbali, M
Curmi, J P
Birnir, Bryndis
Gage, P W

January 1997

Benzodiazepines, which are widely used clinically for relief of anxiety and for sedation, are though...

Relative Positioning of Classical Benzodiazepines to the γ2 Subunit of GABA-A Receptors

Middendorp, SJ
Hurni, E
Schönberger, Matthias
Stein, M
Pangerl, M
Trauner, D
Sigel, E

August 2014

GABAA receptors are the major inhibitory neurotransmitter receptors in the brain. Benzodiazepine exe...

Relative Positioning of Classical Benzodiazepines to the γ2 Subunit of GABA-A Receptors

Middendorp, S.J.
Hurni, E.
Schönberger, Matthias
Stein, M.
Pangerl, M.
Trauner, D.
Sigel, E.

August 2014

GABAA receptors are the major inhibitory neurotransmitter receptors in the brain. Benzodiazepine exe...

Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs

Baur, Roland
Tan, Kelly R
Lüscher, Benjamin P
Gonthier, Anne
Goeldner, Maurice
Sigel, Erwin

January 2008

Classical benzodiazepines, for example diazepam, interact with alpha(x)beta(2)gamma(2) GABA(A) recep...

Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs

Baur, Roland
Tan, Kelly R.
Lüscher, Benjamin P.
Gonthier, Anne
Goeldner, Maurice
Sigel, Erwin

January 2008

Classical benzodiazepines, for example diazepam, interact with alpha(x)beta(2)gamma(2) GABA(A) recep...

Current potentiation by diazepam but not GABA sensitivity is determined by a single histidine residue

Kleingoor, C.
Wieland, H.
Korpi, E.
Seeburg, P.
Kettenmann, H.

February 1993

AB THE GABAA/benzodiazepine receptor is the principal inhibitory neurotransmitter receptor in the ma...

Conductance of recombinant GABA(A) channels is increased in cells co-expressing GABA(A) receptor-associated protein

Everitt, AB
Luu, T
Cromer, B
Tierney, ML
Birnir, Bryndis
Olsen, RW
Gage, PW

January 2004

High conductance gamma- aminobutyric acid type A ( GABA(A)) channels (> 40 picosiemens ( pS)) have b...

Current potentiation by diazepam but not GABA sensitivity is determined by a single histidine residue

Kleingoor, C.
Wieland, H.
Korpi, E.R.
Seeburg, P.H.
Kettenmann, H.

February 1993

The GABAA/benzodiazepine receptor is the principal inhibitory neurotransmitter receptor in the mamma...

Selective modulation of different GABA(A) receptor isoforms by diazepam and etomidate in hippocampal neurons

Abstract

Extracted data

Selective modulation of different GABA(A) receptor isoforms by diazepam and etomidate in hippocampal neurons

Abstract

Extracted data

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