Topics
thymidineChemical substance
smooth muscleAnatomical structure
platelet-derived growth factor (PDGF)Biomolecule
suraminChemical substance
antineoplasticTelevision station
receptorBiomolecule
proteoglycanProtein
Objectives: Suramin is a polysulfonated naphthylurea with antiparasitic and potential antineoplastic activity. Suramin's pharmacological actions, which have not yet been fully elucidated, include antagonism of the action of platelet-derived growth factor (PDGF) at its receptor. We investigated the effects of suramin on PDGF-stimulated proteoglycan synthesis. Methods: Human vascular smooth muscle cells (VSMCs) were incubated in the presence and absence of PDGF and suramin with [3H]thymidine or 35SO4 as radiolabels
The aim of the present study was to test the ability of the chemotherapeutic agent suramin to inhibi...
International audienceSuramin, a hexasulfonated naphtylurea recently used as an anti-tumor drug, is ...
Suramin, a polyanionic compound originally synthesized for use as an antiparasitic agent, has recent...
Objectives: Suramin is a polysulfonated naphthylurea with antiparasitic and potential antineoplastic...
Objectives Suramin is a polysulfonated naphthylurea with antiparasitic and potential antineoplastic...
grantor: University of TorontoThe post-procedural development of restenosis remains the ma...
Platelet-derived growth factor (PDGF) receptor signalling is implicated in cardiovascular diseases s...
Platelet-derived growth factor (PDGF) receptor signalling is implicated in cardiovascular diseases s...
[[abstract]]Fibroblast growth factors (FGFs) play crucial roles in the regulation of key cellular pr...
textabstractSuramin, a non‐specific growth factor antagonist, is currently under investigation for t...
<p>BrdU incorporation and cell count data are shown for quiescent cells incubated with PDGF, FGF2, o...
Previous studies have shown that suramin is capable ofdisrupt-ing autocrine growth involving coexpre...
Objectives Suramin is an old drug used for the treatment of African sleeping sickness. We investigat...
The present experiment was undertaken to study what types of human cancers are responsive to the ant...
BACKGROUND:Pulmonary hypertension (PH) is a progressive disorder characterized by an increase in pul...
The aim of the present study was to test the ability of the chemotherapeutic agent suramin to inhibi...
International audienceSuramin, a hexasulfonated naphtylurea recently used as an anti-tumor drug, is ...
Suramin, a polyanionic compound originally synthesized for use as an antiparasitic agent, has recent...
Objectives: Suramin is a polysulfonated naphthylurea with antiparasitic and potential antineoplastic...
Objectives Suramin is a polysulfonated naphthylurea with antiparasitic and potential antineoplastic...
grantor: University of TorontoThe post-procedural development of restenosis remains the ma...
Platelet-derived growth factor (PDGF) receptor signalling is implicated in cardiovascular diseases s...
Platelet-derived growth factor (PDGF) receptor signalling is implicated in cardiovascular diseases s...
[[abstract]]Fibroblast growth factors (FGFs) play crucial roles in the regulation of key cellular pr...
textabstractSuramin, a non‐specific growth factor antagonist, is currently under investigation for t...
<p>BrdU incorporation and cell count data are shown for quiescent cells incubated with PDGF, FGF2, o...
Previous studies have shown that suramin is capable ofdisrupt-ing autocrine growth involving coexpre...
Objectives Suramin is an old drug used for the treatment of African sleeping sickness. We investigat...
The present experiment was undertaken to study what types of human cancers are responsive to the ant...
BACKGROUND:Pulmonary hypertension (PH) is a progressive disorder characterized by an increase in pul...
The aim of the present study was to test the ability of the chemotherapeutic agent suramin to inhibi...
International audienceSuramin, a hexasulfonated naphtylurea recently used as an anti-tumor drug, is ...
Suramin, a polyanionic compound originally synthesized for use as an antiparasitic agent, has recent...
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