Age-associated changes in muscle activity during isometric contraction

Introduction: We investigated the effect of age on the complexity of muscle activity and the variance in the force of isometric contraction. Methods: Surface electromyogram (sEMG) from biceps brachii muscle and force of contraction were recorded from 96 subjects (20-70 years) during isometric contractions. Results: There is a reduction in the complexity of sEMG associated with aging. The relationship of age and complexity was approximated using a bilinear fit, with the average knee point at 45 years. There was an age-associated increase in the coefficient of variance (CoV) of the force of muscle contraction, and this increase was correlated with the decrease in complexity of sEMG (r 2 = 0.76). Discussion: There is age-associated increase in CoV and also reduction in the complexity of sEMG. The correlation between these two factors can be explained based on the age-associated increase of motor unit density