Harnessing electric fields for microfluidics - From lightning sparks to tiny tornadoes

The dominance of surface tension and viscous effects over body forces such as inertia, gravity or centrifugal force makes fluid actuation and particle manipulation at microscale dimensions extremely difficult. We demonstrate the possibility of exploiting electric fields to drive unstable turbulent-like flows for micro-mixing and complex flows for efficient particle separation and concentration. In particular, the ions resulting from the breakdown of air surrounding a theoretically singular sharp electrode tip due to corona discharge is employed to accelerate the air towards the surface of a liquid in a cylindrical microchamber. Through interfacial shear, the surface liquid layer is recirculated to produce a Batchelor-type flow within the chamber that spirals suspended colloidal particles to a stagnation point at the bottom no-slip plane. We show the use of this technology for rapid and efficient separation of red blood cells from plasma for the development of miniaturised point-of-care diagnostics. Such liquid flows also become unstable at high applied voltages and frequencies leading to the generation of vortices that span a cascade of length scales, which can be exploited for micro-mixin