A gene expression signature for insulin resistance
- Konstantopoulos, N
- Foletta, V
- Segal, D
- Shields, K
- Sanigorski, A
- Windmill, K
- Swinton, C
- Connor, T
- Wanyonyi, S
- Dyer, T
- Fahey, R
- Watt, R
- Curran, J
- Molero - Navajas, J
- Krippner, G
- Collier, G
- James, D
- Blangero, J
- Jowett, J
- Walder, K
Publication date
January 2011
DOI Publisher
American Physiological Society (United States) ISSN
1094-8341 Citation count (estimate)
17Abstract
Insulin resistance is a heterogeneous disorder caused by a range of genetic and environmental factors, and we hypothesize that its etiology varies considerably between individuals. This heterogeneity provides significant challenges to the development of effective therapeutic regimes for long-term management of type 2 diabetes
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