A computational study of astrocytic glutamate influence on post-synaptic neuronal excitability - Fig 6

<p><b>Stability diagram of astrocytic calcium activity in the (a) soma and (b) perisynaptic process, [Ca</b>^<b>2+</b><b>]</b>_<b>ast</b>, <b>on frequency of periodic presynaptic firing activity under different baseline astrocytic level [Glu]</b>_{<b>ast,eq</b>}. (o) denotes upper and lower amplitudes of oscillation at steady state. Lower bound of induced oscillatory regime is increased with decreasing [Glu]_ast,eq. Demonstrates a clear range of input presynaptic firing frequencies which result in Ca²⁺ activation across the three measured [Glu]_ast,eq. where increasing [Glu]_ast,eq correlates with reduction in the lower limit of this range.