MOESM14 of Deletion of HP1γ in cardiac myocytes affects H4K20me3 levels but does not impact cardiac growth

Additional file 14: Fig. S10. Effect of HP1γ KO on ISO-induced heart growth. ISO (5 μg/g) was injected subcutaneously once a day for 6 days and hearts were harvested. Same volume of saline was injected as a vehicle control. Since there was no difference of HW normalized by BW at base line, all genotype of animals with vehicle injection are grouped as a vehicle control group. Upon ISO treatment, all genotype showed a significant increase in HW/BW compared to vehicle control; however, there was no difference between genotype, indicating that HP1γ KO doesn’t have a significant effect on ISO-induced heart growth. * p < 0.05 vs vehicle control