Additional file 5: Fig. S3. Densitometry quantification of WB. Five biological replicates each genotype were used for densitometry quantification analysis. Protein expression level is show as relative expression value against WT. * p < 0.05
RATIONALE: A delicate balance between protein synthesis and degradation maintains cardiac size and f...
Additional file 2: Figure S1. Deletion of UTX/JMJD3, EZH2, or UTX/EZH2 alters global H3K27me3 levels...
Rationale: With a prevalence of 1 in 200 individuals, hypertrophic cardiomyopathy (HCM) is thought t...
Additional file 1: Fig. S1. HP1 localization with H3K9me3. Cardiac myocytes were isolated from 10 we...
Additional file 11: Fig. S7. (A) Quantification of cardiac cross section area after TAC. More than 1...
Additional file 8: Table S1. Comparison of cardiac function in HP1γ KO mouse. Echo cardiograms were ...
Additional file 14: Fig. S10. Effect of HP1γ KO on ISO-induced heart growth. ISO (5 μg/g) was inject...
Additional file 9: Fig. S6. Principle component analysis. RNA-seq was performed using purified CMs i...
Additional file 6: Fig. S4. Localization of heterochromatic histone marks (A) and HP1s (B). 8-wk CMs...
Additional file 12: Fig. S8. No difference in cycling CM in HP1γ KO heart. TAC or Sham surgeries wer...
Additional file 13: Fig. S9. Upregulated genes in HP1Îł KO in both sham and TAC. RT-qPCR was perform...
Additional file 7: Fig. S5. (A) No difference in DNA damage marker in HP1γ KO CMs. Nuclear extracts ...
Abstract Background Heterochromatin, which is formed when tri-methyl lysine 9 of histone H3 (H3K9me3...
RATIONALE: A delicate balance between protein synthesis and degradation maintains cardiac size and f...
RATIONALE: A delicate balance between protein synthesis and degradation maintains cardiac size and f...
RATIONALE: A delicate balance between protein synthesis and degradation maintains cardiac size and f...
Additional file 2: Figure S1. Deletion of UTX/JMJD3, EZH2, or UTX/EZH2 alters global H3K27me3 levels...
Rationale: With a prevalence of 1 in 200 individuals, hypertrophic cardiomyopathy (HCM) is thought t...
Additional file 1: Fig. S1. HP1 localization with H3K9me3. Cardiac myocytes were isolated from 10 we...
Additional file 11: Fig. S7. (A) Quantification of cardiac cross section area after TAC. More than 1...
Additional file 8: Table S1. Comparison of cardiac function in HP1γ KO mouse. Echo cardiograms were ...
Additional file 14: Fig. S10. Effect of HP1γ KO on ISO-induced heart growth. ISO (5 μg/g) was inject...
Additional file 9: Fig. S6. Principle component analysis. RNA-seq was performed using purified CMs i...
Additional file 6: Fig. S4. Localization of heterochromatic histone marks (A) and HP1s (B). 8-wk CMs...
Additional file 12: Fig. S8. No difference in cycling CM in HP1γ KO heart. TAC or Sham surgeries wer...
Additional file 13: Fig. S9. Upregulated genes in HP1Îł KO in both sham and TAC. RT-qPCR was perform...
Additional file 7: Fig. S5. (A) No difference in DNA damage marker in HP1γ KO CMs. Nuclear extracts ...
Abstract Background Heterochromatin, which is formed when tri-methyl lysine 9 of histone H3 (H3K9me3...
RATIONALE: A delicate balance between protein synthesis and degradation maintains cardiac size and f...
RATIONALE: A delicate balance between protein synthesis and degradation maintains cardiac size and f...
RATIONALE: A delicate balance between protein synthesis and degradation maintains cardiac size and f...
Additional file 2: Figure S1. Deletion of UTX/JMJD3, EZH2, or UTX/EZH2 alters global H3K27me3 levels...
Rationale: With a prevalence of 1 in 200 individuals, hypertrophic cardiomyopathy (HCM) is thought t...