Additional file 13: Fig. S9. Upregulated genes in HP1Îł KO in both sham and TAC. RT-qPCR was performed to confirm differential gene expressed detected by RNA-seq. Two-way ANOVA followed by multiple comparison demonstrated that genotype has significant effect on Cyp2b10 and Dlgap1 expression, but not TAC operation or interaction between genotype and TAC operation
AbstractOBJECTIVESThe goal of this study was to identify genes upregulated in the heart in human pat...
altered cardiac function and remodeling after chronic left ventricular pressure overload. ablation ...
As there is a lack of information on the cellular transcriptional regulation of cardiomyogenesis in ...
Additional file 11: Fig. S7. (A) Quantification of cardiac cross section area after TAC. More than 1...
Additional file 14: Fig. S10. Effect of HP1γ KO on ISO-induced heart growth. ISO (5 μg/g) was inject...
Additional file 12: Fig. S8. No difference in cycling CM in HP1γ KO heart. TAC or Sham surgeries wer...
Additional file 5: Fig. S3. Densitometry quantification of WB. Five biological replicates each genot...
Additional file 1: Fig. S1. HP1 localization with H3K9me3. Cardiac myocytes were isolated from 10 we...
Additional file 9: Fig. S6. Principle component analysis. RNA-seq was performed using purified CMs i...
Additional file 7: Fig. S5. (A) No difference in DNA damage marker in HP1γ KO CMs. Nuclear extracts ...
Additional file 8: Table S1. Comparison of cardiac function in HP1γ KO mouse. Echo cardiograms were ...
Abstract Background Heterochromatin, which is formed when tri-methyl lysine 9 of histone H3 (H3K9me3...
Additional file 6: Fig. S4. Localization of heterochromatic histone marks (A) and HP1s (B). 8-wk CMs...
Heterochromatin, which is formed when tri-methyl lysine 9 of histone H3 (H3K9me3) is bound by hetero...
<p>(A) qRT-PCR showing the expression of key cardiovascular genes in <i>tmem88</i>Δ8 mutants compare...
AbstractOBJECTIVESThe goal of this study was to identify genes upregulated in the heart in human pat...
altered cardiac function and remodeling after chronic left ventricular pressure overload. ablation ...
As there is a lack of information on the cellular transcriptional regulation of cardiomyogenesis in ...
Additional file 11: Fig. S7. (A) Quantification of cardiac cross section area after TAC. More than 1...
Additional file 14: Fig. S10. Effect of HP1γ KO on ISO-induced heart growth. ISO (5 μg/g) was inject...
Additional file 12: Fig. S8. No difference in cycling CM in HP1γ KO heart. TAC or Sham surgeries wer...
Additional file 5: Fig. S3. Densitometry quantification of WB. Five biological replicates each genot...
Additional file 1: Fig. S1. HP1 localization with H3K9me3. Cardiac myocytes were isolated from 10 we...
Additional file 9: Fig. S6. Principle component analysis. RNA-seq was performed using purified CMs i...
Additional file 7: Fig. S5. (A) No difference in DNA damage marker in HP1γ KO CMs. Nuclear extracts ...
Additional file 8: Table S1. Comparison of cardiac function in HP1γ KO mouse. Echo cardiograms were ...
Abstract Background Heterochromatin, which is formed when tri-methyl lysine 9 of histone H3 (H3K9me3...
Additional file 6: Fig. S4. Localization of heterochromatic histone marks (A) and HP1s (B). 8-wk CMs...
Heterochromatin, which is formed when tri-methyl lysine 9 of histone H3 (H3K9me3) is bound by hetero...
<p>(A) qRT-PCR showing the expression of key cardiovascular genes in <i>tmem88</i>Δ8 mutants compare...
AbstractOBJECTIVESThe goal of this study was to identify genes upregulated in the heart in human pat...
altered cardiac function and remodeling after chronic left ventricular pressure overload. ablation ...
As there is a lack of information on the cellular transcriptional regulation of cardiomyogenesis in ...