Representative images.

<p>A-C: T2*WI images showing mild spinal cord compression at C4-5, including: A) probabilistic SCT maps of GM (green) and WM (red) registered directly to anatomical images to calculate T2*WI WM/GM signal intensity ratio; B) baseline assessment; C) 13-month follow-up showing no change in the degree of spinal cord compression. Corresponding DTI FA maps (D-F) and MTR maps (G-I) are displayed demonstrating probabilistic WM maps (red, D, G); baseline assessments (E, H); and follow-up images (F, I). Visual inspection does not show obvious differences, but the quantitative readout (averaged over several slices) indicated progressive tissue injury including significant deterioration in composite score (t = -4.1), MTR of the rostral cord (z = -3.0), and T2*WI WM/GM of the rostral cord (z = -4.0). FA also showed a trend toward a decrease in the rostral cord (z = -2.3). CSA: cross-sectional area; DTI: diffusion tensor imaging; FA: fractional anisotropy; GM: grey matter; MTR: magnetization transfer ratio; T2*WI: T2*-weighted imaging; WM: white matter.